A method for identifying a compound that modulates a metastatic lung cancer-associated polypeptide, the method comprising the steps of: (i) contacting the compound with a metastatic breast cancer-associated polypeptide, the polypeptide encoded by a polynucleotide that selectively hybridizes to a nucleic acid sequence at least 80% identical to a sequence selected from those listed in Tables 6A-12C and (ii) determining the functional effect of the compound upon the polypeptide.Ģ1. The method of claim 18, wherein the functional effect is determined by measuring ligand binding to the polypeptide.Ģ0. A method for identifying a compound that modulates a metastatic breast cancer-associated polypeptide, the method comprising the steps of: (i) contacting the compound with a metastatic breast cancer-associated polypeptide, the polypeptide encoded by a polynucleotide that selectively hybridizes to a nucleic acid sequence at least 80% identical to a sequence selected from those listed in Tables 1A-5C, 11A-12C and (ii) determining the functional effect of the compound upon the polypeptide.ġ9. A method of detecting antibodies specific to metastatic lung cancer in a patient, the method comprising contacting a biological sample from the patient with a polypeptide encoded by a nucleic acid comprising a sequence selected from those listed in Tables 6A-12C.ġ8. A method of detecting antibodies specific to metastatic breast cancer in a patient, the method comprising contacting a biological sample from the patient with a polypeptide encoded by a nucleic acid comprising a sequence selected from those listed in Tables 1A-5C, 11A-12C.ġ7. The method of claim 14, wherein the antibody is labeled.ġ6. A method of detecting a metastatic breast cancer or metastatic lung cancer cell in a biological sample, the method comprising contacting the biological sample with an antibody of claim 11.ġ5. The antibody of claim 11, wherein the antibody is a humanized antibodyġ4. The antibody of claim 11, wherein the antibody is an antibody fragment.ġ3. An antibody that specifically binds a polypeptide of claim 10.ġ2. An isolated polypeptide which is encoded by a nucleic acid sequence selected from those listed in Tables 1-12.ġ1. A host cell comprising the expression vector of claim 8.ġ0. An expression vector comprising the nucleic acid of claim 7.ĩ. An isolated nucleic acid molecule consisting of a polynucleotide sequence selected from those listed in Tables 1-12.Ĩ. The method of claim 1, wherein the polynucleotide is immobilized on a solid surface.ħ. The method of claim 1, wherein the polynucleotide or the biological sample is labeled.Ħ. The method of claim 1, wherein the biological sample comprises isolated nucleic acids.ĥ. The method of claim 1, wherein the metastatic cancer-associated transcript is a metastatic breast cancer-associated transcript.Ĥ. The method of claim 1, wherein the metastatic cancer-associated transcript is a metastatic lung cancer-associated transcript.ģ. A method of detecting a metastatic breast cancer or metastatic lung cancer-associated transcript in a cell, the method comprising contacting a biological sample with a polynucleotide that selectively hybridizes to a nucleic acid sequence at least 80% identical to a sequence selected from those listed in Tables 1-12.Ģ.
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